看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。0 ?0 h5 L, ]) w# K
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Currently available feasibility data for possible combination strategies. + Y# b: o. Z" e, T
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Combination Feasibility according to preliminary data 9 ~( |& d; b7 Q* B: o; N# ]$ `
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Bevacizumab + sorafenib Yes, reduced dose
, Z. z% ~3 j( aBevacizumab + sunitinib† No
( L0 k- Z4 j% w3 e0 _Bevacizumab + temsirolimus Yes 8 O4 _! M( E; R6 R+ t6 r
Bevacizumab + everolimus Yes 8 ~; o: ?* h# [0 q; o
Sorafenib + sunitinib ?
$ j7 [- L+ g/ v: f2 W! ?; LSorafenib + temsirolimus Yes, reduced dose
# l# S5 R6 c- J' l5 I3 VSorafenib + everolimus Yes, reduced dose
7 u" R$ g! e8 mSunitinib + temsirolimus† No 1 D8 a) v! L' J: l9 x: N4 o+ f
Sunitinib + everolimus ? ; `5 e6 j( ~9 L1 v$ O J, q* E
Temsirolimus + everolimus ?
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; R7 m* T; v2 h. ^$ p8 I†Led to US FDA warning.
; Z( A: c: \2 R( s?: As yet unattempted combination.) P; p# _: g1 X# U) a
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